Fig. 2

Single-cell RNA analyses of SCCOHT. A, UMAP representation of 8 clusters generated from all tumor cells. The left panel represents the classification of cell types, while the right panel illustrates the specific samples from which these cells originate. B, Violin plots presenting the expression level for the selected markers in different clusters. C, Expression levels of representative well-known markers across the cell types in SCCOHT. Color key from gray to red indicates relative expression levels from low to high. D, Heatmap of the copy number variations in the cancer cells analyzed by the InferCNV pipeline. E, Ratio of cellular composition in the specific patient sample