Fig. 3
From: Icariside II induces ferroptosis through the down-regulation of SLC7A11 in ovarian cancer
Effects of SLC7A11-plasmid and Icariside II on SKOV3 cell proliferation, apoptosis, migration, and invasion. (A) SKOV3 cell proliferation was analyzed using the EdU assay. (B) Apoptosis was assessed by flow cytometry. (C) Quantification of apoptotic SKOV3 cells. (D) Western blot analysis of Bax and Bcl-2 expression. (E and F) Bax and Bcl-2 mRNA levels were analyzed using qRT-PCR. (G) Cell migration was evaluated using a wound-healing assay. (H) Transwell assays showing the invasive capacity of SKOV3 cells. **P < 0.01 vs. Control; ##P < 0.01 vs. Icariside II + control-plasmid