Fig. 7
Targeting MCU rescues FOXJ2 overexpression-induced mitochondrial calcium overload and apoptosis in KGN cells. A Quantitative analysis of the mean fluorescence intensity of Rhod-2AM (indicating mitochondria Ca2+ levels) in KGN cells of each group using flow cytometry. Data are presented as the mean ± SEM (n = 3). ***P < 0.001. ****P < 0.0001. B, C Representative flow cytometry images (B) and corresponding quantitative analysis (C) of apoptosis levels in KGN cells from each group. Data are presented as the mean ± SEM (n = 3). ***P < 0.001. ****P < 0.0001. D, E Representative flow cytometry images (D) and quantitative analysis (E) of apoptosis levels in KGN cells of each group. Data are presented as the mean ± SEM (n = 3). * P < 0.05. ***P < 0.001. ****P < 0.0001