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Table 1 Basis characteristics of training group and validation group

From: Construction and evaluation of machine learning-based prediction model for live birth following fresh embryo transfer in IVF/ICSI patients with polycystic ovary syndrome

Characteristics

ALL(n = 1062)

Training group (n = 743)

Validation group (n = 319)

P

Female age (year)

31 (28, 33)

31 (28, 33)

31 (28, 33)

0.828

Male age (year)

32 (30, 35)

32 (30, 35)

32 (30, 35)

0.889

BMI(kg/m2), n(% )

   

0.316

 <28

889 (83.71)

628 (84.52)

261(81.82)

 

 ≥ 28

173 (16.29)

115 (15.48)

58(18.18)

 

Infertility duration (year), n(% )

   

0.295

 <3

477 (44.92)

342 (46.03)

135 (42.32)

 

 ≥ 3

585 (55.08)

401 (53.97)

184 (57.68)

 

Number of treatments

1 (1, 3)

1 (1, 3)

1 (1, 3)

0.195

Basal FSH (IU/L)

5.72 (4.88, 6.62)

5.74 (4.90, 6.62)

5.69 (4.88, 6.65)

0.529

Basal LH (IU/L)

6.55 (5.55, 7.95)

6.45 (5.55, 7.85)

6.65 (5.61, 8.25)

0.149

Basal PRL (ng/mL)

14.90 (10.70, 21.10)

14.50 (10.60, 20.80)

15.50 (11.30, 21.95)

0.082

Basal E2 (pg/mL)

29.00 (23.00, 39.00)

29.00 (23.00, 39.00)

29.00 (22.00, 39.00)

0.587

T (ng/mL)

0.40 (0.34, 0.49)

0.41 (0.34, 0.50)

0.40 (0.34, 0.49)

0.346

AFC

18 (15, 21)

18 (15, 21)

18 (15, 21)

0.432

AMH (µg/L)

6.74 (5.64, 8.46)

6.71 (5.61, 8.42)

6.82 (5.69, 8.68)

0.359

Fertilization, n(% )

   

0.737

 IVF

788 (74.20)

554 (74.56)

234 (73.35)

 

 ICSI

274 (25.80)

189 (25.44)

85 (26.65)

 

Initial dose of Gn

125 (112.50, 150)

125 (112.50, 150)

125 (112.50, 150)

0.680

Total dose of Gn

2250 (1800.00, 2787.50)

2237.50 (1800.00, 2762.50)

2250.00 (1775.00, 2906.25)

0.577

Dosing days of Gn

12 (11, 14)

12 (11, 14)

12 (11, 14)

0.819

FSH on HCG day (IU/L)

10.56 (8.57, 13.03)

10.62 (8.64, 13.06)

10.46 (8.51, 12.95)

0.946

LH on HCG day (IU/L)

1.00 (0.70, 1.50)

1.00 (0.80, 1.50)

1.04 (0.70, 1.50)

0.551

E2 on HCG day (pg/mL)

3223.00(2263.25, 4259.00)

3267.00 (2314.50, 4326.00)

3143.00 (2200.00, 4203.50)

0.392

P on HCG day (ng/mL)

0.66 (0.46, 0.98)

0.65 (0.47, 0.91)

0.67 (0.44, 1.02)

0.881

Endometrial thickness on

HCG day(mm)

11.85 (10.50, 13.00)

11.80 (10.50, 13.00)

12.00 (10.45, 13.00)

0.820

Trigger strategy, n(% )

   

0.353

rHCG

409 (38.51)

282 (37.95)

127 (39.81)

 

GnRH-a combined with HCG

653(61.49)

461 (62.05)

192 (60.19)

 

Number of oocytes retrieved

13.00 (10.00, 17.00)

13.00 (10.00, 17.00)

14.00 (11.00, 18.00)

0.153

Number of mature oocytes

8.00 (5.00, 11.00)

8.00 (5.00, 11.00)

7.00 (5.00, 12.00)

0.787

Number of fertilized eggs

10.00 (7.00, 13.00)

10.00 (7.00, 13.00)

10.00 (8.00, 14.00)

0.077

Number of high-quality Cleavage embryos

5.00 (3.00, 8.00)

5.00 (3.00, 8.00)

6.00 (3.00, 9.00)

0.104

Stage of embryos transferred, n(%)

   

0.540

 Cleavage

927 (87.29)

645 (86.81)

282 (88.40)

 

 Blastocyst

135 (12.71)

98 (13.19)

37 (11.60)

 

Number of embryos transferred, n(% )

   

0.613

 1

356 (33.52)

245 (32.97)

111 (34.80)

 

 2

706 (66.48)

498 (67.03)

208 (65.20)

 

Live Birth, n(%)

   

0.639

 yes

466 (43.88)

330 (44.41)

136 (42.63)

 

 no

596 (56.12)

413 (55.59)

183 (57.37)

 
  1. Note: Continuous variables are presented as medians (P25, P75), and categorical data were reported as numbers (%). *P < 0.05 was considered statistically significant. BMI: body mass index, FSH: follicle stimulating hormone, LH: luteinizing hormone, E2: Estradiol, T: testosterone, AMH: anti Müllerian hormone, AFC: antral follicle count, Gn: gonadotropin, hCG: human chorionic gonadotropin, P: progesterone, GnRH-a: gonadotropin-releasing hormone agonist
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Journal of Ovarian Research

ISSN: 1757-2215

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