Characteristics | ALL(n = 743) | Live birth group (n = 330) | Control group (n = 413) | P |
---|---|---|---|---|
Female age (year) | 31 (28, 33) | 30 (28, 32) | 32 (29, 34) | < 0.001 |
Male age (year) | 32 (30, 35) | 32 (30, 34) | 33 (30, 36) | < 0.001 |
BMI(kg/m2), n(% ) |  |  |  | < 0.001 |
 <28 | 628 (84.52) | 300 (90.9) | 328 (79.42) |  |
 ≥ 28 | 115 (15.48) | 30 (9.1) | 85 (20.58) |  |
Infertility duration (year), n(% ) | Â | Â | Â | <0.001 |
 <3 | 342 (46.03) | 180 (54.55) | 162 (39.23) |  |
 ≥ 3 | 401 (53.97) | 150 (45.45) | 251 (60.77) |  |
Number of treatments | 1 (1, 3) | 1 (1, 3) | 1 (1, 3) | 0.08 |
Basal FSH (IU/L) | 5.74 (4.9, 6.62) | 5.68 (4.85, 6.5) | 5.84 (4.94, 6.65) | 0.155 |
Basal LH (IU/L) | 6.45 (5.55, 7.85) | 6.55 (5.65, 7.75) | 6.45 (5.55, 7.95) | 0.825 |
Basal PRL (ng/mL) | 14.5 (10.6, 20.8) | 15.65 (10.9, 21) | 13.6 (10.4, 20.4) | 0.074 |
Basal E2 (pg/mL) | 29 (23, 39) | 29 (22.25, 38) | 29 (23, 40) | 0.506 |
T (ng/mL) | 0.40 (0.34, 0.49) | 0.40 (0.33, 0.47) | 0.41 (0.34, 0.52) | 0.002 |
AFC | 18 (15, 21) | 18 (15, 21) | 18 (16, 20) | 0.98 |
AMH (µg/L) | 6.71 (5.61, 8.42) | 6.73 (5.58, 8.43) | 6.7 (5.64, 8.4) | 0.806 |
Fertilization, n(% ) | Â | Â | Â | 0.807 |
 IVF | 554 (74.56) | 248 (75.15) | 306 (74.09) |  |
 ICSI | 189 (25.44) | 82 (24.85) | 107 (25.91) |  |
Initial dose of Gn | 125 (112.5, 150) | 125 (112.5, 150) | 137.5 (112.5, 150) | < 0.001 |
Total dose of Gn | 2237.5 (1800, 2762.5) | 2175 (1825, 2675) | 2300 (1775, 2800) | 0.535 |
Dosing days of Gn | 12 (11, 14) | 12 (11, 14) | 12 (11, 13) | 0.056 |
FSH on HCG day (IU/L) | 10.62 (8.64, 13.06) | 10.3 (8.36, 12.48) | 10.84 (8.82, 13.44) | 0.018 |
LH on HCG day (IU/L) | 1 (0.8, 1.5) | 1 (0.8, 1.5) | 1 (0.79, 1.52) | 0.787 |
E2 on HCG day (pg/mL) | 3267 (2314.5, 4326) | 3213 (2372.25, 4287.25) | 3317 (2232, 4332) | 0.774 |
P on HCG day (ng/mL) | 0.65 (0.47, 0.91) | 0.6 (0.41, 0.85) | 0.69 (0.5, 1) | 0.003 |
Endometrial thickness on HCG day(mm) | 11.8 (10.5, 13) | 12 (10.53, 13) | 11.6 (10.3, 13) | 0.483 |
Trigger strategy, n(% ) | Â | Â | Â | 0.476 |
 rHCG | 282 (37.95) | 129 (39.09) | 153 (37.05) |  |
 GnRH-a combined with HCG | 461 (62.05) | 201 (60.91) | 260 (62.95) |  |
Number of oocytes retrieved | 13 (10, 17) | 13 (10, 16.75) | 14 (10, 18) | 0.228 |
Number of mature oocytes | 8 (5, 11) | 8 (5, 12) | 8 (4, 11) | 0.064 |
Number of fertilized eggs | 10 (7, 13) | 10 (7, 13) | 10 (7, 13) | 0.417 |
Number of high-quality Cleavage embryos | 5 (3, 8) | 5 (4, 8) | 5 (3, 8) | 0.014 |
Stage of embryos transferred, n(%) |  |  |  | < 0.001 |
 Cleavage | 645 (86.81) | 245 (74.24) | 400 (96.85) |  |
 Blastocyst | 98 (13.19) | 85 (25.76) | 13 (3.15) |  |
Number of embryos transferred, n(% ) |  |  |  | < 0.001 |
 1 | 245 (32.97) | 86 (26.06) | 159 (38.5) |  |
 2 | 498 (67.03) | 244 (73.94) | 254 (61.5) |  |