Fig. 1

Hypothalamic pituitary ovarian (HPO) axis dysfunction increasing pulsatile secretion of gonadotropin releasing hormone and insulin leading to the formation of polycystic ovaries and hyperandrogenism
Hypothalamic pituitary ovarian (HPO) axis dysfunction increasing pulsatile secretion of gonadotropin releasing hormone and insulin leading to the formation of polycystic ovaries and hyperandrogenism