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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Proanthocyanidins delaying the premature ovarian insufficiency through regulatory sirt1-p53-p21 signaling pathway in female germline stem cells

Fig. 6

Effects of PACs on Sirt1-p53-p21 mRNA and protein (A) Effect of PACs on the expression of Sirt1-p53-p21 mRNA; **P < 0.01, compared with the control group; (B, C) Effect of PACs on the expression of Sirt1-p53-p21 protein and their relative content; *P < 0.05, **P < 0.01, compared with the control group; (D) EX527, a Sirt1 inhibitor, had a negative effect on FGSCs proliferation, *** P < 0.001, 24 h comparison with the control group; ### P < 0.001, 48 h comparison with the control group; $$$ P < 0.001, 72 h comparison with the control group; (E-H) Effect of PACs on the expression of MVH/OCT4 and Sirt1-p53-p21 mRNA; **P < 0.01, compared with the control group; #P<0.05, ##P<0.01, ### P < 0.001, compared with the EX527 group

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Journal of Ovarian Research

ISSN: 1757-2215

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