Fig. 1

Schematic diagram of mice grouping. The mice were randomly assigned into four groups (n = 8 in each group): Mice in Group 1 were treated with corn oil for six weeks as control. Mice in Group 2 were exposed to 200 mg/kg/d TOCP for four weeks and then received corn oil for two weeks. Mice in Group 3 were exposed to 200 mg/kg/d TOCP for four weeks and then received 25 mg/kg/d tanshinone IIA for two weeks. Mice in Group 4 were exposed to 200 mg/kg/d TOCP for four weeks and then received 50 mg/kg/d tanshinone IIA for two weeks