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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome

Fig. 4

Effects of ZP1 and ZP3 mutations on ZP protein interactions and secretion. (A) Interaction of ZP1WT/ZP1G477X with ZP2 was evaluated by Co-IP with an anti-HA antibody. (B) Interaction of ZP3WT/ZP3D242Y/ZP3N272S/ZP3D242Y + ZP3N272S with ZP2 was evaluated by Co-IP with an anti-FLAG antibody. (C-D) The ZP1 and ZP3 levels in the medium were measured by ELISA. Data are represented as the mean ± SEM; *P < 0.05

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Journal of Ovarian Research

ISSN: 1757-2215

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